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Year : 2022  |  Volume : 66  |  Issue : 1  |  Page : 83-85

Herpes zoster following vaccination with ChAdOx1 nCoV-19 Coronavirus vaccine (recombinant)

1 Assistant Professor, Department of Dermatology, GMC, Palakkad, Kerala, India
2 Associate Professor and HOD, Department of Dermatology, GMC, Palakkad, Kerala, India
3 Junior Resident, Department of Dermatology, GMC, Palakkad, Kerala, India

Correspondence Address:
Anupa Mary Job
“Madhootty House”, Palace Buildings, GB Road, Palakkad - 678 001, Kerala
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijph.ijph_2017_21

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Ever since the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, science has unraveled much knowledge on SARS-CoV-2 which has led to extraordinary and unprecedented progress in developing COVID-19 vaccines. Several adverse cutaneous reactions, ranging from more common local injection site reaction, neutrophilic and pustular drug reactions to flare-up of preexisting dermatoses, have been reported with currently available vaccines. We report a case series of 7 patients who developed herpes zoster (HZ) following the first dose of ChAdOx1 nCoV-19 coronavirus vaccine (recombinant). HZ following vaccination is a rare entity. The occurrence of HZ in the patients presented in this series within the time window 1–21 days after vaccination defined for increased risk and postulated dysregulation of T-cell-mediated immunity, suggests that the ChAdOx1 nCoV-19 coronavirus vaccine (recombinant) could probably be a trigger for reactivation of varicella zoster virus to cause HZ in them.

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