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BRIEF RESEARCH ARTICLE
Year : 2021  |  Volume : 65  |  Issue : 3  |  Page : 294-297

Effect of vitamin-D supplementation on self-perceived health-related quality of life in postmenopausal women in Ludhiana, Punjab


1 Assistant Professor, Department of Community Medicine, Malankara Orthodox Syrian Church Medical College, Ernakulam, Kerala, India
2 Professor and Head of Department, Department of Community and Family Medicine, All India Institute of Medical Sciences, Kalyani, West Bengal, India
3 Professor and Head of Department, Department of Community Medicine, Believers Church Medical College, Tiruvalla, Kerala, India

Correspondence Address:
Nimila Elsa Mathews
Department of Community Medicine, Malankara Orthodox Syrian Church Medical College, Kolenchery, Ernakulam - 682 311, Kerala
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijph.IJPH_226_21

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Postmenopausal women are routinely prescribed calcium and Vitamin-D supplements in view of their increased risk of osteoporosis and fractures. A community-based interventional study was undertaken to determine the effect of Vitamin-D supplementation on self-perceived health-related quality of life in 290 postmenopausal women over 6 months in 2015. Vitamin D (60,000 IU) was supplemented for 8 weeks. The CDC-Health-Related Quality-of-Life Questionnaire -14 was administered to the subjects at baseline and post intervention. The pre and postintervention responses were compared using Chi-square test and paired t-test as appropriate. There was a significant improvement in their overall general health status. Mean systolic blood pressure (BP) was reduced by 3.0% (P = 0.0705) and the mean diastolic BP by 3.2% (P = 0.0419). Post supplementation, high serum Vitamin-D levels was observed in 6.5% of the 92 subjects tested. Prescribing Vitamin D to postmenopausal women without checking the serum levels prior to supplementation may occasionally lead to toxicity.


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