| CASE REPORT |
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| Year : 2020 | Volume
: 64
| Issue : 1 | Page : 93-95 |
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Sickle cell disease presenting in the third trimester of pregnancy: Delayed detection heralding a public health problem?
Ankita Sharma1, Kavita Gaur2, Vandana Puri Tiwari3, Shailaja Shukla4
1 Senior Resident, Department of Pathology, Lady Hardinge Medical College, New Delhi, India
2 Assistant Professor, Department of Pathology, Lady Hardinge Medical College, New Delhi, India
3 Associate Professor, Department of Pathology, Lady Hardinge Medical College, New Delhi, India
4 Director Professor, Department of Pathology, Lady Hardinge Medical College, New Delhi, India
Correspondence Address:
Kavita Gaur
Department of Pathology, Lady Hardinge Medical College, Shaheed Bhagat Singh Marg, New Delhi - 110 001
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/ijph.IJPH_223_19
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We report the case of a 22-year-old primigravida detected as having sickle cell disease (SCD), initially presenting in the third trimester (30th week) of pregnancy. The patient came to our center with a complaint of severe lower limb pain. The peripheral smear showed marked anisopoikilocytosis, numerous leptocytes, sickle cells, and target cells. High-performance liquid chromatography corroborated the diagnosis of SCD, showing a significant peak in the sickle window. The patient was conservatively managed and delivered a healthy baby through normal vaginal delivery. Delayed presentation of SCD in the third trimester of pregnancy is unusual. This report aims to bring attention to the possible causes of such a lag in detection. We also suggest measures to refine the antenatal healthcare screening at multiple levels, with regard to the detection of sickle cell hemoglobinopathy.
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