Users Online: 2156 Home Print this page Email this page Small font sizeDefault font sizeIncrease font size


Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
Year : 1985  |  Volume : 29  |  Issue : 3  |  Page : 206-9

Poliomyelitis surveillance in Delhi.

Correspondence Address:
S Khare

Login to access the Email id

Source of Support: None, Conflict of Interest: None

PMID: 3835138

Rights and PermissionsRights and Permissions

This article summarizes laboratory analyses of serum samples collected at New Delhi's Kalawati Saran Children's Hospital, a center for research on poliomyelitis. The analysis of 1462 serum samples processed for antibody level against polio types 1, 2, and 3 in primary monkey kidney cell lines indicated a predominance of type 1 infection in New Delhi until 1978 and after 1981; in the interim period, type 2 predominated. In addition, seroconversion studies were carried out after 3 and 5 doses of oral polio vaccine. The seroconversion rates for types 1, 2, and 3 polio were 63%, 75%, and 75%, respectively, after 3 doses and 89%, 94%, and 97%, respectively, after 5 doses. Seroconversion rates were significantly higher in the winter than in the summer months. Analysis of 1652 cases of polio in 1977-81 in which children had been vaccinated revealed an overall polio prevalence rate of 6.2/1000 after the 1st dose, 3.2/1000 after the 2nd dose, and 4.7/1000 after the 3rd dose. A further analysis of 36 serum samples collected from normal adults found that only 4 samples were negative to antibodies against all 3 types of polio virus. Finally, random testing of the potency of oral polio vaccine batches has indicated that all have a satisfactory titer. A 1981 survey of 24,840 children in Delhi 5-9 years of age found a poliomyelitis prevalence rate of 5.88/1000; the onset of disease was 3 years of age and under in 82% of cases.

[PDF Not available]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded0    
    Comments [Add]    

Recommend this journal